First of all sodium do not act as a functional group and second sodium has high tendencyto form bond with high electronegative element.Carbon is not an electronegative element.
The other mentioned functional groups in the question such as hydoxyl group,phosphate group and carbonyl group can easily form bond with carbon atom.
look for any bleeding or sores. look at the red legs. diagnosis with red leg disease. prescribe antibiotics orally. follow up in a week. meanwhile keep the frog away from other frogs.