A physical change is basically a body change so like if a crayon is solid then sits in the sun for a long time it melts away that’s a physical change because it changes its physical appearance
Answer:
d. more permeable to sodium ions.
Explanation:
The binding of Acetylcholine with the receptors at motor end plate facilitate membrane permeability to sodium ions therefore opening of voltage gated channels for sodium ions.
Sodium ions diffused into the synapse of post synaptic neuron at the neuromuscular junction.
If the stimulus is up to threshold levels; more chemical(neurotransmitter) gated sodium channels opens, and sodium ions move into the synapse to depolarize the membrane with reversal of charges to generate action potential.
The continuous binding of Acetycholine , leads to permanent opening of sodium ions,and over excitation from depolarization. Acetycholinesterase enzymes breakdown Acetycholine to choline and Acetyl Co -A. These are recycle back to Acetycholiine
The mechanism of action of Bordetella pertussis is to stop the cilia of epithelial cells from beating.
<em>Bordetella pertussis</em> is a pathogenic, gram-negative bacteria. It is the causative agent of highly communicable respiratory disease known as pertussis or whooping cough.
The mechanism of action of Bordetella pertussis:
- This bacterium colonizes the ciliated epithelial cells of the respiratory airways of the host.
- A surface protein on the bacteria called filamentous haemagglutinin adhesin binds to sulfatides on the cilia of epithelial cells. When the bacterium is anchored, it releases tracheal cytotoxin, which prevents the cilia from beating.
- As a result, the cilia in an organism's lungs are unable to sweep out foreign material, and the body reacts by causing the host to cough. When people cough, bacteria are released into the air, where they might spread to other hosts.
- Another toxin called the pertussis toxin, often known as PTx, prevents adenylate cyclase from using ATP to convert to cyclic AMP. This results in over-conversion of ATP to cyclic AMP, which may interfere with cellular signaling systems. As a result, phagocytes are unable to respond to an infection effectively.
Know more about <em>Bordetella pertussis</em> here:
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Answer:
I'm not quite sure but I'll try and figure it out if I don't get back to you I'm sorry but I will try.
Explanation:
