1. Catherine the great was the Empress of Russia.
2. She was the longest ruler to have lived.
3. She had affairs with members of her government.
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In short your answer would be.... probably It was the first time the Supreme Court declared an act of Congress unconstitutional, since the others don't make sense.
Answer:
C. Its effects stopped all advancements in science and medicine for the next two centuries.
Explanation:
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Spiro Agnew was accused of taking bribes and forced to resign as Vice President of the United States. The charges stemmed from corrupt activity as a public official in Maryland.