Question

A researcher is studying different mutations in yeast. He isolates one yeast strain that fails to properly form replisomes. When he assesses the DNA sequences of genes encoding yeast helicase and ORC, he cannot find any mutations. What other gene(s) might be mutated in this yeast strain?
DnaA
Cdc6
Cdt1
β clamp
both Cdc6 and Cdt1

Answer 1

Answer:

The correct answer is "both Cdc6 and Cdt1"

Explanation:

The replisome is a complex molecular system that allows for the replication of DNA in yeast. There are multiple genes that participate in the replisome function, however if a researcher finds out that a yeast strain fails to properly form replisomes it is very likely that the genes that might be mutated are both Cdc6 and Cdt1. Cdc6 and ORC are the genes that send the signal to the yeast to start the replisome formation, and Cdt1 is a DNA replication factor that if it is mutated it could cause that yeast is not able to form the replisome.