Prokaryotes are the single-celled organisms of domain bacteria and archaea which lacks a nucleus and membrane-bound organelle while eukaryotic cells are the organisms which contains a well defined nucleus and other membrane bound organelles.
The fundamental difference between prokaryotes and eukaryotes is the presence of DNA(genetic material) in a membrane-bound organelle called nucleus which is absent in prokaryotes where genetic material is stored in an area called nucleoid which is not surrounded by the nuclear membrane.
The compartmentalisation of DNA confers stability to the cell as genetic material is protected from the external bodies and injuries.
