Answer:
12 molecules of ATP can be made from one molecule of acetyl CoA.
Explanation:
If one molecule of acetyl CoA enter TCA cycle then it result in the formation of 3 molecules of NADH,1 molecule of FADH2 and 1 molecule of GTP that is equivalent to 1 molecule of ATP.
Now the reducing equivalent such as NADH and FADH2 enters electron transport chain and get oxidized to regenerate NAD+ and FAD along with ATP. 1 molecule of NADH produces 3 molecules of ATP whereas 1 molecule of FADH2 produces 2 molecules of ATP.
So that net gain of ATP is given below
3 molecules of NADH = 9 molecules of ATP
1 molecule of FADH2 =2 molecules of ATP
1 molecule of GTP = 1 molecule of ATP
As a result total 12 molecules of ATP is by the oxidation of 1 Acetyl CoA by TCA cycle .
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