Nicotine on direct application in humans causes irritation and burning sensation in the mouth and throat, increased salivation, nausea, abdominal pain, vomiting and diarrhea. Predominant immediate effects consist of increase in pulse rate and blood pressure. Nicotine also causes an increase in plasma free fatty acids, hyperglycemia, and an increase in the level of catecholamines in the blood. There is reduced coronary blood flow but an increased skeletal muscle blood flow. The increased rate of respiration causes hypothermia, a hypercoagulable state, decreases skin temperature, and increases the blood viscosity.
For amphetamine the immediate effects are quicker reaction times, feelings of energy/wakefulness, excitement, increased attentiveness and concentration, feelings of euphoria. Side effects of amphetamines can include heart palpitations, dry mouth, headache, hostility, nausea, cognitive impairment, severe anxiety, lack of appetite, teeth grinding, dizziness, increased heart rate, heart palpitations, rapid breathing rate, hypertension (high blood pressure), increased body temperature, erectile dysfunction, irregular heartbeat.
Cocaine causes a short-lived, intense high that is immediately followed by the opposite intense depression, edginess and a craving for more of the drug the side effects are Loss of appetite increased heart rate, blood pressure, body temperature, contracted blood vessels increased rate of breathing, dilated pupils, disturbed sleep patterns, nausea, hyperstimulation, bizarre, erratic, sometimes violent behavior hallucinations, hyperexcitability, irritability, tactile hallucination that creates the illusion of bugs burrowing under the skin, intense euphoria, anxiety and paranoia, depression, intense drug craving, panic and psychosis, convulsions, seizures and sudden death from high doses (even one time)
A: No
E: Because, of the placental mammals, apes are in the group Euarchontoglires and bears are in Laurasiatheria. Yes they’re both animals but, they are not even closely related.
Answer:
In order to be useful in treating human infections, antibiotics must selectively target bacteria for eradication and not the cells of its human host. Indeed, modern antibiotics act either on processes that are unique to bacteria--such as the synthesis of cell walls or folic acid--or on bacterium-specific targets within processes that are common to both bacterium and human cells, including protein or DNA replication. Following are some examples.
Most bacteria produce a cell wall that is composed partly of a macromolecule called peptidoglycan, itself made up of amino sugars and short peptides. Human cells do not make or need peptidoglycan. Penicillin, one of the first antibiotics to be used widely, prevents the final cross-linking step, or transpeptidation, in assembly of this macromolecule. The result is a very fragile cell wall that bursts, killing the bacterium. No harm comes to the human host because penicillin does not inhibit any biochemical process that goes on within us.
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