Answer:
The correct option is C) cytosolic, endoplasmic reticulum
<em>New membrane phospholipids are synthesized by enzymes bound to the cytosolic side of the endoplasmic reticulum membrane. </em>
Explanation:
Synthesis of proteins that are destined to membrane or exportation starts in the cytoplasm with the production of a molecule portion known as a signal aminoacidic sequence. This signal sequence is located in the amino extreme of the synthesizing protein, and when it reaches a certain length, it meets the signal recognizing particle. This particle joins the signal sequence of the protein and leads the synthesizing protein and associated ribosome to a specific region in the Rough endoplasmic reticulum where it continues the protein building. When they reach the membrane of the endoplasmic reticulum, the signal recognizing particle links to a receptor associated with a pore. Meanwhile, the ribosome keeps synthesizing the protein, and the enlarged polypeptide chain goes forward the reticulum lumen through the pore. While this is happening, another enzyme cuts the signal sequence, an action that requires energy from the ATP hydrolysis. When the new protein synthesis is complete, the polypeptide is released into the reticulum lumen. Here it also happens the protein folding (which is possible by the formation of disulfide bridges of proteins are formed) and the initial stages of glycosylation (the oligosaccharide addition). The newly synthesized proteins get packaged into vesicles that take them to the Golgi apparatus.
In the Golgi complex, proteins suffer their final association with carbohydrates and lipids to originate glycoproteins and glycolipids. Once these processes are done, the glycoproteins and glycolipids are packaged again into new vesicles that drive them to their final destiny.
Answer:
d. Estrogen will bind to a receptor protein that enters the nucleus and activates specific genes.
Explanation:
Estrogens are small lipophilic molecules synthesized from cholesterol. This steroid hormone (estrogen) is able to directly enter into the cell nucleus to bind with their corresponding receptors. Subsequently, estrogen-receptor binding stimulates these receptors to form dimeric structures that bind to DNA and thus activate gene expression. Estrogen receptors interact with DNA and activate gene expression through zinc finger domains composed of four (4) cysteine residues surrounding a zinc atom.
Answer:
2 electrons
Explanation:
According to the octet rule, atoms must bond to each other, sharing electrons among themselves in an attempt to complete their valence shell (last layer of the electrosphere). In other words, an atom becomes stable when it has 8 electrons in its valence shell.
Oxygen atoms have six electrons in their valence shell, so to achieve the stability suggested by the octet rule (eight electrons), these atoms share two electrons, forming one oxygen gas (O₂) molecule.
When was BSE first discovered?
BSE first appeared in British cattle in the mid-1980s. There have been numerous cases detected in other countries. A complete list of countries is available from both the U.S. Food and Drug Administration (FDA) and the U.S. Department of Agriculture (USDA).
<h3><u>Answer;</u></h3>
Gene therapy to correct defective genes that cause diseases.
<h3><u>Explanation</u>;</h3>
- Gene therapy refers to the procedure that involves the introduction of nucleic acids (DNA or RNA) into the cells of an organism for the purpose of correcting abnormalities, such as a mutations or in other words to treat a genetic disease.
- Gene therapy entails bringing a normal and functional gene known as a trans-gene into a cell with altered gene. Another method can bring RNA capable of partially regulating or blocking the expression of an altered gene.
- The nucleic acids are introduced into the patient's cells by means of a viral vector or injected directly into the cells in the form of naked DNA.
