The greatest attack against ratification of the Constitution was over what issue? It only represented some of the states and not the nation. It favored the northern interests over the southern interests. It did not abolish slavery.
The greatest attack against ratification of the constitution would be "it did not abolish slavery.It only represented some of the states and not the nation. It favored the northerner states and not the southern states.
It was primarily "men" and "children" who formed the largest part of the factory labor force during the Industrial Revolution, since much of this took place before the government started regulating things like harsh labor conditions and child labor.