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dem82 [27]
3 years ago
10

Which of the following correctly describes how the baroreceptor reflexes would respond to a fall in blood pressure?The cardioinh

ibitory center would be stimulated.The vasomotor center would increase sympathetic output to arterial smooth muscle to increase TPR.Contractility would decrease and heart rate would increase.Baroreceptors would be stimulated and send increased impulses to the cardiovascular control center in the medulla.The cardioacceleratory center would increase parasympathetic output to the heart.
Biology
1 answer:
irinina [24]3 years ago
8 0

The correct answer is: The vasomotor center would increase sympathetic output to arterial smooth muscle to increase TPR.

Baroreceptors are mechanoreceptors (sensors or modified nerve endings) found in the blood vessels and their function is to detect the change in blood pressure and participate in the regulation of it (so that proper blood pressure can be maintained). The action of baroreceptors or baroreflex works as a negative feedback loop: when the blood pressure is decreased, baroreflex activation also decreases (baroreceptors are active even at normal blood pressures) and causes heart rate to increase.

Decreased blood pressure leads to lower baroreceptor “firing” which then results in an increase in sympathetic stimulation of the heart and sympathetic stimulation of the peripheral vessels, resulting in vasoconstriction. As a result blood pressure increase.

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Answer:

1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).

2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).

Explanation:

In sickle cell anemia, a change in the DNA nucleotide sequence is observed, where adenine is substituted by thymine, whose expression is the change in the amino acid sequence of globine β, incorporating valine instead of glutamic acid. This represents a molecular mutation - point mutation - by subtitution, which corresponds to missense mutation.

<u>Normal hemoglobin protein in a RBC</u>

DNA                 CTG ACT CCT GAG GAG AAG TCT

Amino acids     Leu  Thr   Pro   Glu   Glu   Lys   Ser

<u>Sickle cell hemoglobin protein in a RBC</u>

DNA                 CTG ACT CCT <em>GTG</em> GAG AAG TCT

Amino acids     Leu  Thr   Pro   <em>Val</em>   Glu   Lys   Ser

When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.

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Thus, the answer is cochlear duct.

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