1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
andrew-mc [135]
3 years ago
12

Normal cells die in a nutrient medium containing thymidine and methotrexate, whereas mutant cells defective in thymidylate synth

ase survive and grow. The mutant cells grow because the medium contains the___________ they are unable to make normal cells, however, continue to synthesize their own and thereby convert their limited supply of to________ . The methotrexate inhibits , so cannot be regenerated. Without a supply of___________ for the synthesis of nucleotides and amino acids, the cells die.
Biology
1 answer:
Dmitry_Shevchenko [17]3 years ago
7 0

Answer:

*Thymidine

*THF to DHF

*THF

Explanation:

Normal cells die in a nutrient medium containing thymidine and methotrexate, whereas mutant cells defective in thymidylate synthase survive and grow. The mutant cells grow because the medium contains the_____Thymidine______ they are unable to make normal cells, however, continue to synthesize their own and thereby convert their limited supply of to__THF to DHF______ . The methotrexate inhibits , so cannot be regenerated. Without a supply of______THF_____ for the synthesis of nucleotides and amino acids, the cells die.

NOTE:

THF means Tetrahydrofolate

DHF means Dihydrofolate

Thymidine which is also reffered to as deoxythymidine, is described as a deoxynucleoside that is composed of the pyrimidine base thymine that is attached to the sugar deoxyribose. Thymidine is a nucleoside made up of pentose sugar, pyrimidine base tymine and deoxyribose, it is one of the the four nucleoside found in exclusively DNA as well as T-loop of tRNA.

Tetrahydrofolate also known as tetrahydrofolic acid can be described as part of folic acid that function as a coenzyme which aid metabolic reactions that includes nucleic acid and amino acids. It is also reffered to as one-carbon metabolism, and it's oone-carbon mechanism is associated to the histidine, serine of amino acid.

You might be interested in
Select all that apply.
Zepler [3.9K]

Answer:

Gamete and bacterial cell.

3 0
3 years ago
Based on molecular clocks, Goodman's phylogeny places the last common ancestor of all primates at ______________________.
VashaNatasha [74]

Answer:

63 MYA

Explanation:

Morris Goodman was a editor-in-chief of the journal Molecular Phylogenetics and Evolution.

In his classification, every organism was traced back to its last common ancestors, and he traced that of primates last common ancestors to be dated as far back as 63 MYA.

3 0
3 years ago
List the signs of sugar addiction
Nezavi [6.7K]

Answer:

headaches, lethargy or feeling tired, cravings, muscle pain, nausea, bloating and even insomnia.

Explanation:

3 0
2 years ago
Read 2 more answers
Whom you think the reason for corona viruses​
morpeh [17]

Answer:

I think freemason leaders

3 0
2 years ago
I need help with Number 12 please
NemiM [27]

Answer: 12.  C

Explanation:

4 0
2 years ago
Other questions:
  • Archaea differ from bacteria in that archaea
    13·1 answer
  • The nurse is obtaining data on an older adult client. what finding may indicate to the nurse the early symptom of heart failure?
    9·1 answer
  • which of the body systems does not rely on the autonomic nervous system to stimulate involuntary events
    11·1 answer
  • Which nutrient provides the highest number of calories per gram?
    8·2 answers
  • What do you think prokaryotes envolver before eukaryotes?
    7·1 answer
  • When the oocyte is released from the ovary, it is transported to the uterus through the?
    12·1 answer
  • Point (-5, 5) lies in Quadrant I II III IV
    6·2 answers
  • 3. Which of the following undergoes change during a chemical reaction? (1 point)
    11·1 answer
  • In the experiment, which of the following variables should remain consistent?
    14·1 answer
  • Which is not part of a neuron? <br>A. dendrites <br>B. axon <br>C. actin sheath <br>D. nucleus​
    9·2 answers
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!