1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
andrew-mc [135]
3 years ago
12

Normal cells die in a nutrient medium containing thymidine and methotrexate, whereas mutant cells defective in thymidylate synth

ase survive and grow. The mutant cells grow because the medium contains the___________ they are unable to make normal cells, however, continue to synthesize their own and thereby convert their limited supply of to________ . The methotrexate inhibits , so cannot be regenerated. Without a supply of___________ for the synthesis of nucleotides and amino acids, the cells die.
Biology
1 answer:
Dmitry_Shevchenko [17]3 years ago
7 0

Answer:

*Thymidine

*THF to DHF

*THF

Explanation:

Normal cells die in a nutrient medium containing thymidine and methotrexate, whereas mutant cells defective in thymidylate synthase survive and grow. The mutant cells grow because the medium contains the_____Thymidine______ they are unable to make normal cells, however, continue to synthesize their own and thereby convert their limited supply of to__THF to DHF______ . The methotrexate inhibits , so cannot be regenerated. Without a supply of______THF_____ for the synthesis of nucleotides and amino acids, the cells die.

NOTE:

THF means Tetrahydrofolate

DHF means Dihydrofolate

Thymidine which is also reffered to as deoxythymidine, is described as a deoxynucleoside that is composed of the pyrimidine base thymine that is attached to the sugar deoxyribose. Thymidine is a nucleoside made up of pentose sugar, pyrimidine base tymine and deoxyribose, it is one of the the four nucleoside found in exclusively DNA as well as T-loop of tRNA.

Tetrahydrofolate also known as tetrahydrofolic acid can be described as part of folic acid that function as a coenzyme which aid metabolic reactions that includes nucleic acid and amino acids. It is also reffered to as one-carbon metabolism, and it's oone-carbon mechanism is associated to the histidine, serine of amino acid.

You might be interested in
The majority of Earth is covered with water. Water takes longer to heat up and cool down which has an impact on the air temperat
pentagon [3]
It is because of high specific heat capacity of water
8 0
3 years ago
Read 2 more answers
How does energy flow through an ecosystem starting with the sun
Andrej [43]

Answer:

The sun gives energy to the producers(plants) then those plants are consumed by other members of an ecosystem for their energy

Explanation:

6 0
3 years ago
I need to know number 7. anything will help
s344n2d4d5 [400]

Answer:

I'm not sure of the answer but I do believe it is C The Great Lakes

5 0
2 years ago
Bacteria undergo an asexual process of cell splitting called binary fission. This process is genetically similar to?
belka [17]
A). Mitosis is correct :)
7 0
3 years ago
Read 2 more answers
What is the purpose of the menisci found in your knee, jaw, shoulders, and wrists? Why might there be a meniscus there but not,
Blababa [14]

Answer: I believe Meniscus tears are not healed on their own.

Explanation:

Because the two most common causes of a meniscus tear are due to traumatic injury (often seen in athletes) and degenerative processes (seen in older patients who have more fragile cartilage). The most common mechanism of a traumatic meniscus tear occurs when the knee joint is flexed and the knee is then twisted.  The meniscus tear can only be surgically removed. However, in some cases people can live with the meniscus tear without any problem. Also, there are exercises that lessen the symptoms of this problem. The most common symptoms of a meniscus tear are: Knee pain, Knee swelling, Tenderness when pressing the meniscus, Popping or clicking inside the knee, Limited knee joint movement.

7 0
3 years ago
Read 2 more answers
Other questions:
  • How do you say "Christmas Day" in French
    6·1 answer
  • If someone got sick with an intestinal infection from eating the yogurt, what type of antibiotics would you prescribe? Why?
    12·1 answer
  • What does DNA stand for? also what does RNA stand for?
    9·2 answers
  • Out of these people who r ur favs?
    5·1 answer
  • In a multi-paragraph essay, explain how the activity of individual neurons enables you to perform a simple action like answering
    14·1 answer
  • In blood clotting, the platelets __________ to initiate the clotting process.
    10·2 answers
  • Some steps in mitosis are shown below. They are not in order.
    14·2 answers
  • What caused the earth to develop layers as it cooled?
    8·2 answers
  • Polypeptides that are transported in vesicles are first made by _____ a ribosomes on the rough endoplasmic reticulum. b the smoo
    7·1 answer
  • During which of the following processes do sister chromatids separate from each other?
    12·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!