Patrick Henry was a leading anti-federalist, believing that the U.S Constitution would diminish the rights of the U.S people and their states. This was one of the motives behind the Bill of Rights.
This answer really depends on which country and how early you are looking at, in terms of which era of explorer.
The answer, broadly, is Christianity.
Depending on the explorer and the country they represent, though, the answer could be Roman Catholicism or Protestantism.
D. Too much regulation could hurt businesses.
