Osama bin Laden the infamous leader of the global terrorist organization Al Qaeda was once an important member of the U.S. backed Mujahadeen in Afghanistan.
It was composed of war captives and Christian youths pressed into service; all the recruits were converted to Islam and trained under the strictest discipline. It was originally organized by Sultan Murad I. The Janissaries gained great power in the Ottoman Empire and made and unmade sultans.
The byzantine empire lost Rome. Rome was claimed by the byzantines in the 6th century and in the 6th century was given to the papacy as the major seat and capitol of the papal state
Watson and Crick is the answer