It is also called the Ellipsoidal Joint
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I believe that is the correct answer
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
Answer:
The correct answer is b. Immunogens
Explanation:
Immunogens are the antigens that can trigger the immune response in the body once gets inside the body. Any antigen having capacity to excite a immune response against them is called immunogens but not every antigen is immunogen.
An antigen is called immunogen when it has some characteristic features like foreignness, high molecular weight and chemical complexity. An immunogen can initiate both innate and adaptive immune response. Adaptive immune response is memory based and very specific for any particular immunogen.
Some common immunogens are: bacteria, virus, drugs, chemicals, dust, toxins.
Answer:
B. Antibiotic B will compete with antibiotic A, making it more likely for bacteria to evolve
antibiotic resistance.
Explanation:
