Bloom syndrome (BS) is a rare autosomal recessive disorder characterized by growth deficiency, immunodeficiency, genomic instability, and the early development of cancers of many types. BLM, the protein encoded by BLM, the gene mutated in BS, is localized in nuclear foci and absent from BS cells. BLM encodes a DNA helicase, and proteins from three missense alleles lack displacement activity. BLM transfected into BS cells reduces the frequency of sister chromatid exchanges and restores BLM in the nucleus. Missense alleles fail to reduce the sister chromatid exchanges in transfected BS cells or restore the normal nuclear pattern. BLM complements a phenotype of a Saccharomyces cerevisiae sgs1 top3 strain, and the missense alleles do not. This work demonstrates the importance of the enzymatic activity of BLM for its function and nuclear localization pattern.
<u><em>What DNA sequence were the researchers trying to detect? </em></u>
<u><em>Are you referring to the choices below?</em></u>
The liver is a chemical scientist in a way processing and expelling chemicals with the buffer system it also process caffeine but too much caffeine will harm the liver.
Note i am not sure if understood your question if this answer is wrong .sorry its probably my fault
Explanation:
sorry, I may use old terms; I believe it is at the hypothalamus, for endocrine system...
The flu vaccine is a medicinal shot which is supposed to prevent/ and or decrease your chances of getting the flu. It is supposedly working as stated by the producers of this vaccine however many children have been given this vaccine and it dosen`t work. The recommendations are appropriate as it is better to be safe than sorry. However there are some negative effects. For example a person would get a cold afterwards and this of course is sickness. Overall, I recommend not highly, but as i stated earlier it is better to be safe than sorry.
