Answer:
C) Loosest
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Coarse means rude or rough.
Thus the word that is best associated with the word coarse is B. Roughness.
Roughness is somehow similar to coarse, it shows cruelty or rudeness in some actions or words. Other term that can be used to describe it is being impolite.
Answer:
Mary gave up on her dream because she could not use her hands which were deteriorating.
Explanation: