Answer:
1. The 2 bases forming each rung of the 'ladder' snap apart. This is caused by an enzyme that passes along the strands, 'unzipping' it
2. Spare nucleotides (in the nucleus of the cell) attach themselves to the 'broken rungs' to repair the break. Each repairing nucleotide is identical to the broken one
3. As each 'broken rung' is repaired, two 'ladders' form, that is 2 identical strands of DNA. The 'repairing' is really the process of replica
Explanation:
Hope this helps!
Long-term potentiation (LTP) is considered a cellular correlate of learning and memory. The presence of G protein-activated inwardly rectifying K(+) (GIRK) channels near excitatory synapses on dendritic spines suggests their possible involvement in synaptic plasticity. However, whether activity-dependent regulation of channels affects excitatory synaptic plasticity is unknown. In a companion article we have reported activity-dependent regulation of GIRK channel density in cultured hippocampal neurons that requires activity oF receptors (NMDAR) and protein phosphatase-1 (PP1) and takes place within 15 min. In this study, we performed whole-cell recordings of cultured hippocampal neurons and found that NMDAR activation increases basal GIRK current and GIRK channel activation mediated by adenosine A(1) receptors, but not GABA(B) receptors. Given the similar involvement of NMDARs, adenosine receptors, and PP1 in depotentiation of LTP caused by low-frequency stimulation that immediately follows LTP-inducing high-frequency stimulation, we wondered whether NMDAR-induced increase in GIRK channel surface density and current may contribute to the molecular mechanisms underlying this specific depotentiation. Remarkably, GIRK2 null mutation or GIRK channel blockade abolishes depotentiation of LTP, demonstrating that GIRK channels are critical for depotentiation, one form of excitatory synaptic plasticity.
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<span>The bruise slowly disappears as the arm heals.
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<span>The two identical daughter cells resulting from mitosis and cytokinesis are identical in the following ways:1. Mitosis occurs when the nucleus of the cell divides into two identical nuclei, each with the same type and number of chromosomes. The cell's DNA is duplicated during this phase. Sometimes the cell's DNA isn't copied properly resulting in cancer-type cells. 2. Cytokinesis is when the cytoplasm divides into two identical daughter cells. Each cell is genetically identical and both are a similar size.
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Hey there!
Here is a simple food chain:
Grass >>> Grasshopper >>> Mouse >>> Owl
Hope this helps!
~Autumly
