Answer:
Post-translational modification, alternative splicing, DNA mutations
Explanation:
The diversity of the proteome can occur at different levels of biological processes:
1. During DNA replication yielding DNA mutations.
2. At the mRNA level in Alternative Splicing.
3. After translation on amino acid molecules including addition of different types of sugars (Glycosylation). This is post-translational modification.
The classic signs of the cushing syndrome include fat accumulation behind the shoulders, known as a buffalo hump, and a round "moon-shaped" face. Cushing's syndrome is a hormonal disorder caused by prolonged exposure of the body's tissue to high levels of the hormone cortisol. The symptoms of this disorder includes; weight gain, obesity, fatty deposits especially in the midsection, the face, and between the shoulders and the upper back.
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