<span>b. The Vicar of Wakefield
</span><span>Samuel Johnson was referring to a group of English lyric poets when he coined the term "metaphysical poets". These poets lived in the seventeenth century. Their work was mainly about love, humour, love and metaphysical conceits. Their poetry was often far-fetched with unusual metaphors or similes. The metaphysical poets wrote very different poetry from the general style of the other poets of their time. They were not interested in writing about the usual images of nature or classical mythology. </span>
Tumor suppressor genes encode for proteins that inhibit or slow the progression of the cell cycle through a specific stage.they also encode for check point control proteins that arrests the cell cycle if the DNA is damaged or the chromosomes are abnormal. Mutation in the tumor suppressor genes that cause a loss or decreased function would lead to uncontrolled cell cycle leading to abnormal proliferation and the cell may become cancerous.