I think it would be the first one
        
             
        
        
        
Answer:
The major problem in The Tale of Despereaux is the unfriendly relationship between the mice, the rats and the humans. Roscuro the rat caused the death of the Queen which forced the King to outlaw all rats.
Explanation:
E
 
        
             
        
        
        
C. They feared the radicals who had taken power in France during the revolution
        
             
        
        
        
Transition words I believe