Answer:
Option A, a drug to treat high blood pressure that reversibly inhibits an enzyme catalyzing production of a chemical that causes blood vessels to contract
Explanation:
The complete question is
If you were working for a pharmaceutical company as part of a drug discovery team, which of these enzyme inhibitors would you suggest as a productive avenue for drug development?
a) a drug to treat high blood pressure that reversibly inhibits an enzyme catalyzing production of a chemical that causes blood vessels to contract
b) a drug to treat diabetes that irreversibly inhibits an enzyme in the metabolic pathway to synthesize glucose
c) a compound that acts as a competitive inhibitor for a digestive enzyme produced only in the presence of certain foods
d) a compound that inhibits enzymes by significantly changing the ph throughout the body
Solution
Productive avenue of a drug simply means producing an drug that not only treats the main disease or disorder but also functions to inhibit the causative agent activity. In case of option A, both the objectives of producing drug are met and hence it is the right choice.
High blood pressure usually affects the blood vessels by narrowing them and in severe cases may rupture them. If a drug as stated in option A is produced, it will not only rectify the effects of high blood pressure but will also prevent the blood vessels from narrowing by inhibiting the activity of enzymes responsible for producing chemical that leads to blood vessel contraction.
Hence, option A is correct
The answer is (C) Replication
Though occasional errors could occur in cells during replication; the cells have error checking and proofing mechanisms that reduce the rate of error to one to several million replications in higher eukaryotes.
After all, one mismatch error during replication would not result in major effects. The others choices, however, have higher rates of causing genetic abnormalities.
When you shiver, that's actually how you help yourself stay warm! It's your immediate instinct reaction to do so when you're cold, so there will be more heat produced, and they occur by your muscles moving. =)
Hey there!
There are different types of nerves. Some of them are sensory nerves like the ones in your hands and feet, and some complete other functions. However, they all originate from somewhere.
Cranial nerves originate from the brain itself, and spinal nerves come from the spinal cord. Damaging any can cause serious injury like death and paralysis. There are 12 cranial nerves in the nervous system, and 10 out of 12 originate in the brain stem.
Hope this helps!