The correct answer is D. for sure.
The leading strand is the strand of nascent DNA which is being synthesized in the same direction as the growing replication fork. A polymerase "reads" the leading strand template and adds complementary nucleotides to the nascent leading strand on a continuous basis.
First, he should measure how long it takes for the liquid to become clear if X and Y are mixed together. Then, he should measure how long it takes if he also adds substance A to X and Y. He will find out if substance A is a catalyst. hope this helps :)