The Spanish lost Florida and this weakened the economy so much that they lost their foothold in Mexico and Latin America also, which greatly impacted their economy. After losing their foothold in the West, Spain faded out of the world spotlight as a superpower.
The answer is loss of land because when the Spanish lost Florida, Mexico, and the Western Territory in the United States. So many people forgot about this country because they lost so much land. The answer is loss of land.
The statement that correctly explains why the European Renaissance began in the Italian city-states would be "<span>A. Their location along the Mediterranean Sea made them major centers of trade," since this allowed the new ideas to spread with relative ease. </span>