A single cell RNA seq analysis identifies 25 population of epidermal cells .
<h3>What is single cell transcriptomics used for?</h3>
Single cell transcriptomics are being used to create reference maps of healthy human tissues, organs and systems at single cell resolution.
An essential model system for studying stem cells and tissue regeneration is the mouse epidermis with its hair follicles. To demonstrate how the cellular heterogeneity of the murine telogen epidermis is controlled at the transcriptional level, we used single-cell RNA-sequencing in this study. 25 different populations of interfollicular and follicular epidermal cells were identified by impartial clustering of 1,422 single-cell transcriptomes. With previously unheard-of resolution, our data allowed for the reconstruction of gene expression patterns during epidermal development and along the proximal-distal axis of the hair follicle.
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