Mostly the spyware and malware protection for desktop and laptop or workstations are to protected with anti-virus regular updates. All workstation or desktop or laptops are to updated operating systems patches.
If any operating systems patched update to be schedule and checked regularly. Schedule scanning by virus scanner to be made for desktop and laptop or workstations in regular interval basis
There are third parties tools such as malware and ADWCLEANER are also available free scanner software through internet where end user can download and scanner so software will clean the malware.
Mostly end user do mistake keep the files in desktop. Most of the malware software will affect the desktop folder only.
It will also affect c:\users folder and register enter keys.
You would want to check for any programs running in the background, as well as run a virus scan.
