Answer:
Ferdinand of Aragon marries Isabella of Castile in Valladolid, thus beginning a cooperative reign that would unite all the dominions of Spain and elevate the nation to a dominant world power. Ferdinand and Isabella incorporated a number of independent Spanish dominions into their kingdom and in 1478 introduced the Spanish Inquisition, a powerful and brutal force of homogenization in Spanish society. In 1492, the reconquest of Granada from the Moors was completed, and the crown ordered all Spanish Jews to convert to Christianity or face expulsion from Spain. Four years later, Spanish Muslims were handed a similar order.
Explanation:
It is B. New European medicines made surviving harsh colonial conditions possible.
The answer is Mecca........
American imperialism revolved around more than just politics and economics and national self-interest. They also included notions of humanitarianism, morality, religion, and ideas of civilization