Answer:
The miRNAs act as post-transcriptional silencers, as they are similar to specific mRNAs and regulate their stability and translation. They are small endogenous non-coding ribonucleic acid (RNA) molecules, with about 22 nucleotides, which act as regulators of gene expression in plants and animals, at the post-transcriptional level through the cleavage of a target messenger RNA (mRNA) or repression of translation.
In general, most miRNA genes are transcribed by RNA polymerase II in the nucleus in primary miRNAs (pri-miRNAs). Individually, a pri-miRNA can produce a single miRNA or contain groups of two or more miRNAs that are processed from a common primary transcript. These long pri-miRNA are cleaved by a complex comprising the double-stranded RNAse III enzyme (DROSHA) and its essential cofactor, the binding protein DGCR8 (DiGeorge Syndrome Critical Region 8 protein) in mammals. DROSHA contains two domains of RNAse III, each of which cleaves a strand of the RNA resulting in the precursor microRNA (pre-miRNA) with about 70 base pairs, which contains a double-stranded stretch and a single-stranded loop, forming a structure in clamp. The pre-miRNA is exported to the cytoplasm by the protein exportin-5 (XPO-5), where it is cleaved by DICER1, an RNAse III that assesses the 3 'and 5' ends of the pre-miRNA, generating a mature miRNA with about 22 nucleotides. The processing of pre-miRNA by Dicer promotes the unfolding of the RNA duplex in the form of a clamp. The position in the formation of the clamp can also influence the choice of tape.
Explanation:
should be called Bilateral symmetry
the answer is b ..........
Explanation:
b
Answer:
B): Gold is in fact heavier than silver. Smaller gold objects will be heavier than silver objects even if they're both the same size.
C): I cannot answer this question because it would be an opinion. Both are good in nutritional value.
Explanation:
Answer:
A
Explanation:
Conduction is the exchange of energy as warmth or power starting with one iota then onto the next inside an article by direct contact. Conduction happens in solids, fluids, and gases. Nonetheless, solids move energy most proficiently since the atoms in solids are most firmly stuffed, and the particles are nearer together, as displayed in this figure. For fluids and gases, the thickness of the particles are by and large lower than those of solids and the particles are farther separated, so the energy move is less productive.
