The world was rapidly developing after world war 2 and with these new innovations, new responsibilities grew. For example, female employment and race issues were a large issue in post WW2 USA and governments had to adapts to accept equality and ongoing change.
I would myself go with The use of tissue and organ transplants or the use of laser technologies to avoid open heart surgery
The rulers of Italy before the Romans were the "Etruscans", although it should be noted that the Etruscan dominance of the region was not even close to the Romans' in terms of power and political nature.