Answer : The dissociation constant of the PFK‑inhibitor complex is, 5 µM
Explanation :
The expression for reversible competitive inhibition when apparent Km affected by addition of the inhibitor is:
![K_m_a=K_m[1+\frac{I}{K_i}]](https://tex.z-dn.net/?f=K_m_a%3DK_m%5B1%2B%5Cfrac%7BI%7D%7BK_i%7D%5D)
where,
= apparent value = 52 µM
= Michaelis–Menten constant = 40 µM
I = inhibitor concentration = 1.5 µM
= dissociation constant of the PFK‑inhibitor complex
Now put all the given values in the above formula, we get:
![52\mu M=40\mu M[1+\frac{1.5\mu M}{K_i}]](https://tex.z-dn.net/?f=52%5Cmu%20M%3D40%5Cmu%20M%5B1%2B%5Cfrac%7B1.5%5Cmu%20M%7D%7BK_i%7D%5D)
Therefore, the dissociation constant of the PFK‑inhibitor complex is, 5 µM
The answer is pyruvate. In the absence of oxygen in
anaerobic respiration, the pyruvate is converted to lactic acid in animals and
ethanol in plants. However, in the presence of oxygen, the pyruvate enters the Krebs
cycle after being converted to Acetyl CoA. Pyruvate is an intermediate product
of glycolysis.
A descriptive observation may very well be a mixture of both quantitative and qualitative as it can utilize elements of both types. Qualitative deals with the kinds of observations that cannot be measured in numerical form. Quantitative data is just that.
It means that only those who are able to adapt with all conditions they are placed in will be able to live.
"Crepuscular" means active at dawn and dusk, so if you wanted to avoid coming across the Gila monster when hiking in Arizona you would want to avoid dawn and dusk.
