The event in Japanese history that is a direct result of the Japanese government signing this treaty is the Fall of the Tokugawa Shogunate.
The fall of the Tokugawa was contributed to a number of direct reasons and indirect reasons; the direct reasons was his inability to deal with the threat of foreign colonial powers, and signing humiliating trade treaties against the will of the nationalist aristocrats and the emperor. Indirect reasons included centuries long grievances from warlords who lost their power under him economic stagnation turning into depression, and development and spread of popular nationalistic, modernist philosophy among the upper classes.
The city of Jerusalem was important for Judaism and Christianity because it is considered the Holy Land. For Islam, it is important because they conquered the land and took it from the Christians and the Jews, and made it their own religious land.
Answer:
They felt the Proclamation was a plot to keep them under the strict control of England and that the British only wanted them east of the mountains so they could keep an eye on them. As a result, colonists rebelled against this law just like they did with the mercantile laws.