Separatists, because they are against any form of government and promote negative liberty
The correct answer to this open question is the following.
The need for raw materials led to further state expansion, following the Manifested Destiny that was the belief for many Americans that God's will was for America to expand its territories. After the Louisiana Purchase of 1803, US President ordered the Lewis & Clark expedition to the new Western territories. When the exédition was over, those explorers went to Washington D.C. to inform the President about the results. That is when Jefferson authorized people to settle those territories, work the land, and exploit the many raw materials and natural resources to get a profit.
The American Revolution change American society socially. The Revolution also unleashed powerful political, social, and economic forces that would transform the post-Revolution politics and society
The solution the Kansas-Nebraska Act of 1854 offered to the problem of slavery was to allow both states to determine their slave or free state status via popular vote. However, both states were widely uninhabited at the time of their admittance and thus a huge number of settlers from free and slave states swarmed upon the states to sway the vote in their favor. This resulted in tragedy in the form of attacks where free and slave supporters clashed in violent and oftentimes deadly confrontation.