Distress is a form of Negative stress
D. Synergistic Interaction
the effect of one medicine is canceled or reduced when taken with another medicine Drug substances other than food that change the structure or function of the body or mind Medicines drugs that are used to treat or prevent diseases or other conditions side effects reactions to medicine other than what is intended Synergistic effect
DNA in the nucleus provides the template to produce messanger RNA which provides the amino acid sequence that will be assembled by the ribosomes into protein molecules. The golgi apparatus will package the protein into the extra-cellular space.
Your primary concern should be their safety. :)