Answer:
In p53 pathways, 3 proteins which are mutate and cause cancer that proteins are:
1.BRCA2
2. p53 in Rb genes binds with deoxyribonucleic acid that stimulates another gene to produce a protein known as p21 that interacts with cdk2. When p21 is combined with cdk2 cell will not pass through to the next stage of cell division. This is Li-Fraumeni syndrome (when p53 causes cancer from parents to offspring)
3.BRCA1
The parent that transmits mutation in one of these genes has a 50% chance of inheriting the mutation. The effects of mutations in BRCA2 and BRCA1 are seen when the person's second copy of the gene is normal.
Answer: c. Point B has an elevation less than 2750 feet.
Explanation:
The lines drawn on the map are known as contour lines and they are used to measure elevation. Point B is on a river and rivers are only able to flow at a lower elevation than the area around them.
Point B is therefore lower than the area around it and as the closest contour line to it puts the area at an elevation of 2,750 feet, that must mean that Point B is lower than 2,750 feet.
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Answer:
An Enhancer
Explanation:
Enhancers are the regulatory sequences and are generally located 80-160 base pairs upstream of the transcription start site. Enhancers have bidirectional elements that are involved in the initiation of transcription. Enhancers serve as the binding sites for activators to increase the concentration of activators in the vicinity of the promoter and thereby increase the rate of transcription of the gene.
According to the given information, the loss of a regulatory sequence led to a reduced level of transcription of the gene. This means that the regulatory sequence was involved in the upregulation of transcription. The presence of the sequence far away from the promoter makes it an enhancer.