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iren2701 [21]
3 years ago
10

g Sickle-cell anemia arises from a mutation in the gene for the beta chain of human hemoglobin. The change from a GAG to a GTG i

n the mutant eliminates a cleavage site for the restriction enzyme MstII, which recognizes the target sequence CCTGAGG. These findings form the basis of a diagnostic test for
Biology
1 answer:
soldier1979 [14.2K]3 years ago
5 0

Answer:

The sickle-cell gene.

Explanation:

The sickle cell mutation is in the gene encoding the β subunit. The sickle cell gene is located on the short arm (p) of chromosome 11, at position 15.5. Sickle cell anemia is a genopathy caused by a single mutation that results in the substitution of an amino acid in the β chains of the tetrameric protein hemoglobin. It characterized by the presence of sickle cells in the bloodstream, which are red cells or sickle-shaped erythrocytes. This form causes difficulty in the circulation of red blood cells. Confirmation of sickle cell anemia is obtained through tests that determine the presence and relative amount of hemoglobin S in a blood sample, that is, by checking the phenomenon of sickle cell disease, in a drop of blood between the slide and covers objects, or the presence of hemoglobin S by means of electrophoresis.

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a. an action potential spreads throughout the Z discs.

b. intercalated discs connect the muscle fibers together.

c. calcium enters the cell from storage chambers called intercalated discs.

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