An invisible line, known as the 180 DEGREE LINE or AXIS OF ACTION, runs through the space of the scene. The camera can shoot from any position within one side of that line, but it may never cross it. This convention ensures that the shot will have consistent spatial relations and screen directions.
I would personally say that "one" would probably give up on life if there is no family(relitives), or if "one" is not financially healthy. Or suffering in types of ways such as, "no legs or arms", so "one" would say "there is no point in life now".