The Anti-Federalists failed to grant the states the majority of the power (in a similar set-up to the Articles of Confederation), if I recall correctly. The important task they achieved was the addition of the Bill of Rights to the Constitution. They wanted to ensure that some of our most important rights were clearly defined and included in our nation's leading document.
Humans gave up razor-sharp claws, fangs, sense and instincts in favor of intelligence. This brain-power has enabled humans to make the ultimate adaptation; that of making the environment adapt to us. We have domesticated crops and livestock, we irrigate, we wear clothes, build shelters, air-condition or heat our homes.
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