The hypothesis by Coleman was that the product of the ob+ gene was the appetite suppressing hormone. Hence, the homozygous ob/ob mutant are in a position to synthesize that hormone, and its circulating level would be zero. He also hypothesized that the product of the db+ gene was the receptor for the appetite-suppressing hormone. Thus, the homozygous db/db mutant would be able to synthesize the hormone but would not be in a position to respond to it. It would eat excessively and produce large amounts of body fat, which in turn would produce large amounts of appetite-suppressing hormone . In the absence of a receptor, the db/db mutant's hormone level would remain abnormally high.
Coleman's hypothesis were confirmed when the precise functions of the ob+ and db+ genes were determined. The peptide hormone encoded by the ob+ gene was named Leptin.
Answer:
The Correct answer is "A stretch of nucleotides within a larger DNA Molecule"
A male grabs the female around her chest with his front legs and clings until she lays her eggs in the water. ... In 2 to 3 weeks the eggs hatch into tadpoles. It can take 3 to 4 months for the tadpoles to absorb their tails, grow legs and develop lungs.
Blue-green algae aka Cyanobacteria
