a rouleau (rouleaux)
<h3>What is a rouleau?</h3>
Red blood cells (RBCs) can stack up or aggregate into rouleaux (singular: rouleau), which are formed by the distinct discoid shape of vertebrate cells. The discoid RBCs' flat surface offers them a lot of surface area to cling to and make contact with, creating a rouleau. Because of them, the ESR (erythrocyte sedimentation rate) increases when the plasma protein concentration is high. This serves as an all-purpose indicator of sickness.
Infections, multiple myeloma, Waldenström's macroglobulinemia, inflammatory and connective tissue disorders, and malignancies are among the illnesses that can result in rouleaux production. As one of the causes of microvascular occlusion in diabetic retinopathy, it also occurs in diabetes mellitus.
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