Búscalo, Wikipedia es bien!!!
It is Big Bang and cannot be proved. A hypotheses must be testable. Big Bang is not testable.
Mutations can affect the coding of "base pairs" in the chromosome of an individual by various means like:
1) by Deletion
2) by Duplication
3) by Translocation
4) by Inversion
After all that changes, codes deviates from normal information & can affect individual in negative way. In that manner, Mutations affect individual traits.
Hope this helps!
A physical change is basically a body change so like if a crayon is solid then sits in the sun for a long time it melts away that’s a physical change because it changes its physical appearance