There are 2 main processes to test tablet hardness: compression testing and 3 point bend testing. For compression testing, the analyst generally aligns the tablet in a repeatable way, and the tablet is squeezed between a fixed and a moving jaw. The first machines continually applied force with a spring and screw thread until the tablet started to break. When the tablet fractured, the hardness was read with a sliding scale.
Based on the dosage available, the amount in mL of the drug required is 22.5 mL.
<h3>What is drug dosage?</h3>
Drug dosage refers to the amount of drug that should be taken by a patient in order to produce effective pharmacodynamic results.
The dosage of the drug to be given is 45 mEq.
The dosage available is 30 mEq in 15 mL.
In order to give this required dosage the amount in mL required is calculated as follows:
30 mEq is in 15 mL
45 mEq will be in x mL
x = 45 * 15/30
x = 22.5 mL
In conclusion, drug dosage refers to the amount of drug required to produce good results in the patient.
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