August Comte is considered the founder of social studies as well as the founder of Sociology. He was the author of the "Law of the Three Stages", or three forms in which human understanding of the world evolves, being the top of it the Positive understanding of the world, which in short words is that based on the knowledge of the scientific rules which command the world and particularly social behaviour.
The industrial revolution, the major changes in the late 18th and early 19th centuries might have evidenced this third stage of thinking on Comte's reading of society, because the situation of political, technological an social changes created a situation of ruling the world by sciences and reason, more than theological or methaphysical conceptions.
Stowe never meant Uncle Tom to be a derided name, but the term as a pejorative has developed based on how later versions of the character, stripped of his strength, were depicted on stage.
The significance of the "Articles of Confederation" lies in that it is the very first written constitution of the United States. The structure of the "Articles" provides for independence and sovereignity of the states, while Congress appears as a last resort for disputes.