That is a picture of Hagia Sophia located in Istanbul, Turkey. The Hagia Sophia served as a center for religious, political, and artistic life for the Byzantine Empire (Eastern Roman Empire). It started as a place of great importance for the Byzantines, but then became a extremely important site of worship when Sultan Mehmed II conquered Constantinople. (Constantinople is modern day Istanbul)
Answer:
D. New diseases were introduced.
Explanation:
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