Indians were in the middle and England could easily access them.
Answer:
- Number of Demands
- Political Situations
- Recent Invention
- Price of a substitute product.
Explanation:
- Number of Demands
As the number of demands increased, the price of the product tend to increase to. As Sellers will try to produce more goods in order to accommodate the demands
- Political Situations
If the good is produced in a country with unstable political situation, there will be less countries that willing to trade with that country. This tend to make the price of the goods in that country tend to increase.
- Recent Invention
If the new inventions are better than the previous product, the consumers will more likely to purchase the new ones over the old product. This will shift the trades to focus on the new product and the price of the old product will decrease.
- Price of a substitute product.
As The price of its substitute increase, the price of that good tend to decrease.
Each enzyme has an "active site". The active site of each enzyme is unique in terms of 3D structure. Each unique active site can be thought of as a 3D surface that is able to bind only a single unique substrate or set of substrates, and it is the shape of the active site that is responsible for each enzyme's substrate selectivity. Most enzymes actually use the same or nearly the same, mechanisms of action; most commonly simple acid-base chemistry is used to catalyse reactions.
It may be difficult to understand, but enzyme active sites are actually thought to bind the "transition state" of the substrate. The transition state may be thought of as a state where the structure of the substrate is literally stretched to be somewhere between the orginal substrate structure, and the structure of the product of the enzyme catalyzed reaction. In other words, the enzyme can be thought of as "pulling" the substrate into a product. In this way, the enzyme lowers the energy required to pass the "transition" state, and accelerates the reaction of substrate to product.
Thus, the structure of the enzyme imparts both its substrate specificity (because only certain substrates will fit into the active site), and its activity (because in binding the substrate, the enzyme lowers the transition energy required for the substrate to form product).
Hope this helped, despite my rambling.
