Theoretical and experimental measurements show that in many cases, the contributions of ionic and hydrogen-bonding interactions
to ΔH for protein folding are close to zero. Provide an explanation for this result. (Hint: Consider the environment in which protein folding occurs.) The formation of favorable ______ ionic or ________ interactions in a _________ protein replace interactions between solvent (water) and the ionic species (or _________donors and acceptors) in the _________ state. The favorable ΔH obtained by formation of ____________ bonds in the ___________ protein is offset by the energy required to ___________ many interactions, with solvent going from the ________ to the ________ state.
Fill in the blanks above using the words listed below.
The formation of favorable intermolecular ionic or H-bonding interactions in a folded protein replace interactions between solvent (water) and the ionic species (or H-bond donors and acceptors) in the unfolded state. The favorable ΔH obtained by formation of intramolecular bonds in the folded protein is offset by the energy required to break many interactions, with solvent going from the unfolded to the folded state.
The formation of favorable C-bond ionic or C-bonding interactions in a folded protein replace interactions between solvent (water) and the ionic species (or restore donors and acceptors) in the unfolded state. The favorable ΔH obtained by formation of H-bond in the H-bonding protein is offset by the energy required to break many interactions, with solvent going from the inter-molecular to the intramolecular state.
hepatic portal vein is a blood vessel that carries blood from the gastrointestinal tract and spleen to the liver. This blood are usually rich in nutrient because it contains extraction from digested materials or food substances in the gastrointestinal tract and it is processed in the liver for removal of toxins before the blood returns to the heart.
