Answer:
Orochimaru
Explanation:
In Naruto. Orochimaru acts as the primary antagonist for the first part of the series. After his parents were killed when he was young, Orochimaru's only source of affection was his teacher, the Third Hokage Hiruzen Sarutobi, and his two teammates.
Madara Uchiha
C. studied
their health
fatigue
general diabilty