The correct answer should be A. He was occupied with making sure his sister did not repeat the same error, otherwise.
This should be the correct answer because placing otherwise here would create confusion in the sentence as it is not sure to what it refers.
Clause Definition:
A part of a sentence that contains a verb.
( Basically it has to do with grammar.)
Drug abuse: increasing awareness on negative effects of drug abuse, and also ignorance.
Joblessness: Government poor policies, and retrenchments that leave many jobless.
Poor parenting: Young adults brought up in broken homes, and young adults from orphanages.
It would be #1, since personal experiences are usually irrelevant in those formats. Hope this helps. :)