The answer to the question stated above is non-disjunction.
The first steps of catabolism generally take place in the cytosol.
Glycolysis and pentose phosphate pathway are metabolic process that occurs inside of the cytosol. Other catabolic processes such as the citric acid cycle, electron transport chain, and oxidative phosphorylation all take place in the mitochondrial membrane.
It is true, it dissolves during prophase because it is not needed in the following phase of metaphase
Cell is limited in size for many reasons. Cells wouldn't be respire effectively if it were too large, because the surface area to the volume ratio would be too small.
The other thing is that if the cell were too large, it would be difficult for it to move nutrients and waste products in and out of the cell. So, cells are limited in size.
Homeostasis is maintained by negative feedback loops within the organism. In contrast, positive feedback loops push the organism further out of homeostasis, but may be necessary for life to occur. Homeostasis is controlled by the nervous and endocrine systems in mammals.