Answer:
padres
Explanation:
You missed the options. Anyway, I give you the only possible answer that fits the question. Below the answer, there is a translation for a better understanding
—Buenos días, ¿dónde está Ana?
—Ana está en la oficina.
—¿Ustedes son los padres de la madre de Ana?
—Sí, somos sus ____padres____.
Translation:
"Good morning, where is Ana?"
"Ana is in the office."
"Are you the parents of Ana's mother?"
"Yes, we are her ____parents____."
Answer:
"sabes"
Explanation:
the sentence is in a present state and the present of the verb "saber" is "sabes"