You might be allergic to the drug or its components. You might have either liver or kidney dysfunction and not be able to metabolize the medication properly, allowing it to build up to toxic levels. You might need to take other drugs along with it to prevent side effects.
World Health Day is observed every year on April 7 since 1950. This day is aimed at creating awareness of a specific health theme and also to highlight a priority area of concern for the World Health Organisation (WHO).