Sedatives and Hypnotics depress the central nervous system by interfering with the transmission of nerve impulses.
Like alcohol, sedatives and hypnotics are depressants that depress the central nervous system. Since long-term exposure to alcohol can lead to the development of depression, chronic use of sedatives and hypnotics, as demonstrated by several neurobiological and imaging studies
Long-term use of sedatives can cause side effects such as Psychiatric disorders such as anxiety.
It has been suggested that treating depression and anxiety with sedatives/hypnotics, especially benzodiazepines, may reduce the risk in the first few weeks. Sedatives/hypnotics also have inhibitory and disinhibitory properties, but these may increase the risk
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Kit Carson served as John C Fremonts guide
<span>This is true. Salespeople do not answer to anyone unless they willingly sign to someone. For the most part salespeople are independent contractors who offer their services or products to the general public. They make their own decisions and control which products or services they want to sell.</span>
-Ming Dynasty.
-Zhu Yuanzhang's army eliminates the military forces of the Yuan Dynasty.
-Zhu declares himself the emperor of China.
-Construction on the Great Wall of China begins.
-Maritime trade is banned in China.
-Construction begins on the Forbidden City.
-The fourth Chinese domination of Vietnam begins.